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Cost-free and conjugated noroxycodone, totally free and conjugated oxycodone, and oxymorphone are excreted in human urine adhering to a single oral dose of oxycodone. The major circulating metabolite is noroxycodone with an AUC ratio of 0.6 relative to that of oxycodone. Oxymorphone is present inside the plasma only in minimal concentrations. The a

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